NEW BRUNSWICK, N.J. – Rutgers researchers have discovered a potential new way to treat childhood epilepsy using a widely available therapeutic drug.
Rutgers neuroscientist Gabriella D’Arcangelo and her colleagues have published their research findings in the journal Disease Models and Mechanisms.
In their quest for new therapeutic approaches, the researchers are investigating the molecular basis of the disease. The article describes the first use of a mouse model of cortical dysplasia, a malformation of the brain that is most often the cause of childhood epilepsy. Introducing the drug rapamycin, originally used to prevent rejection in organ transplants, suppressed epileptic seizures in the mice
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